ARID1B Polyclonal Antibody

Background:
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
6A3 5, ARID 1B, ARID domain containing protein 1B, AT rich interactive domain 1B (SWI1 like), AT rich interactive domain 1B, AT rich interactive domain containing protein 1B, BAF 250b, BAF-associated factor, 250-KD, B, BAF250b, BRG1 associated factor 250b, BRG1 binding protein, BRG1 binding protein ELD/OSA1, BRG1 binding protein hELD/OSA1, BRIGHT, DAN 15, DAN15, Eld (eyelid)/Osa protein, ELD/OSA1, hELD/OSA1, hOsa 2, hOsa2, KIAA1235, MRD12, OSA 2, Osa homolog 2, OSA2, OTTHUMP00000040115, p250R, RP11 419L10.1

Immunogen: Synthetic peptide of human ARID1B

Swissprot: Q8NFD5
Gene Accession: NP059989

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.