ARL2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2305a
Background:
ADP-ribosylation factors (ARFs) regulate intracellular vesicular membrane trafficking and stimulate a phospholipase D isoform. ARL (ADP-ribosylation like factor) proteins are very similar in sequence to ARFs. ARFs and ARF-like (ARL) proteins, which share sequence similarity with ARFs, form a subfamily of the Ras-related GTPase superfamily. ARL2 encodes a ubiquitiously expressed 184-amino acid predicted protein that is 76% identical to ARF1 and 40 to 45% identical to the Drosophila ARL proteins. Recombinant ARL2 binds to GTP rapidly but guanine nucleotide exchange does not require phospholipids, which is a characteristic of the ARF proteins.
Other Names:
ADP-ribosylation factor-like protein 2, ARL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2305a was selected from the N-term region of human ARL2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ARL2
Gene ID: 402
Primary Accession: P36404
Other Accession: NP_001658
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
ADP-ribosylation factors (ARFs) regulate intracellular vesicular membrane trafficking and stimulate a phospholipase D isoform. ARL (ADP-ribosylation like factor) proteins are very similar in sequence to ARFs. ARFs and ARF-like (ARL) proteins, which share sequence similarity with ARFs, form a subfamily of the Ras-related GTPase superfamily. ARL2 encodes a ubiquitiously expressed 184-amino acid predicted protein that is 76% identical to ARF1 and 40 to 45% identical to the Drosophila ARL proteins. Recombinant ARL2 binds to GTP rapidly but guanine nucleotide exchange does not require phospholipids, which is a characteristic of the ARF proteins.
Other Names:
ADP-ribosylation factor-like protein 2, ARL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2305a was selected from the N-term region of human ARL2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ARL2
Gene ID: 402
Primary Accession: P36404
Other Accession: NP_001658
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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