ARMC8 Polyclonal Antibody

Background:
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1, 100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
Armadillo repeat containing protein 8, Armadillo repeat-containing protein 8, ARMC8, ARMC8, HSPC056, MGC10058, MGC4880, S863 2

Immunogen: Fusion protein of human ARMC8

Swissprot: Q8IUR7
Gene Accession: BC013424

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.