ARP Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES4039
Catalog Number: ELK-ES4039
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
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Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
mesencephalic astrocyte derived neurotrophic factor(MANF) Homo sapiens The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014],
Alternative Names:
MANF, ARMET, ARP, Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MANF. AA range:11-60
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 20
GeneID: MANF
Storage: -20°C/1 year
NOTE: For Research Use Only
mesencephalic astrocyte derived neurotrophic factor(MANF) Homo sapiens The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014],
Alternative Names:
MANF, ARMET, ARP, Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MANF. AA range:11-60
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 20
GeneID: MANF
Storage: -20°C/1 year
NOTE: For Research Use Only
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