ARP rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014],response to unfolded protein, response to organic substance, response to protein stimulus,

Synonyms: MANF, ARMET, ARP, Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET

Gene Name: MANF

Gene ID: 7873

SwissProt ID: P55145

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.