ARP1 homolog A polyclonal, anti-human

Background:
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Other Names:
Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog, ACTR1A, CTRN1

Antigen Types:
Synthetic Peptide

Gene Name:
ACTR1A (HGNC:167)
Gene ID:
10121
Primary Accession: P61163
Other Accession: NP_005727;10121;54130 (mouse);