ARPC1B Polyclonal Antibody

Background:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Research Area: Signal transduction

Synonyms:
Actin related protein 2/3 complex subunit 1B 41kDa , Actin related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 1B, ARC1B, ARC41, Arp2/3 complex 41 kDa subunit, ARP2/3 protein complex subunit p41 , Arpc1b, p40 ARC, p41 ARC, p41-Arc

Immunogen: Fusion protein of human ARPC1B

Swissprot: O15143
Gene Accession: BC002562

Calculated MW: 41 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.8 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.