ARRB1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12005b
Background:
Members of arrestin/beta-arrestin protein family arethought to participate in agonist-mediated desensitization ofG-protein-coupled receptors and cause specific dampening ofcellular responses to stimuli such as hormones, neurotransmitters,or sensory signals. Arrestin beta 1 is a cytosolic protein andacts as a cofactor in the beta-adrenergic receptor kinase (BARK)mediated desensitization of beta-adrenergic receptors. Besides thecentral nervous system, it is expressed at high levels inperipheral blood leukocytes, and thus the BARK/beta-arrestin systemis believed to play a major role in regulating receptor-mediatedimmune functions. Alternatively spliced transcripts encodingdifferent isoforms of arrestin beta 1 have been described, however,their exact functions are not known.
Other Names:
Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Gene Name: ARRB1
Gene ID: 408
Primary Accession: P49407
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Members of arrestin/beta-arrestin protein family arethought to participate in agonist-mediated desensitization ofG-protein-coupled receptors and cause specific dampening ofcellular responses to stimuli such as hormones, neurotransmitters,or sensory signals. Arrestin beta 1 is a cytosolic protein andacts as a cofactor in the beta-adrenergic receptor kinase (BARK)mediated desensitization of beta-adrenergic receptors. Besides thecentral nervous system, it is expressed at high levels inperipheral blood leukocytes, and thus the BARK/beta-arrestin systemis believed to play a major role in regulating receptor-mediatedimmune functions. Alternatively spliced transcripts encodingdifferent isoforms of arrestin beta 1 have been described, however,their exact functions are not known.
Other Names:
Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Gene Name: ARRB1
Gene ID: 408
Primary Accession: P49407
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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