ARRB1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP12005B
Catalog Number: AC-AP12005B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31615
Applications: WB, FC, IF, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31615
Applications: WB, FC, IF, IHC-P
Datasheet
Request Information
Background:
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.
Other Names:
Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Target/Specificity:
This ARRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1.
Antigen Region:
336-363
Antigen Type: Synthetic Peptide
Gene Name: ARRB1
Gene ID: 408
Primary Accession: P49407
NCBI Accession: NP_004032.2;NP_064647.1
Other Accession: P29066; Q95223; Q8BWG8; P17870; NP_004032.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.
Other Names:
Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1
Target/Specificity:
This ARRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1.
Antigen Region:
336-363
Antigen Type: Synthetic Peptide
Gene Name: ARRB1
Gene ID: 408
Primary Accession: P49407
NCBI Accession: NP_004032.2;NP_064647.1
Other Accession: P29066; Q95223; Q8BWG8; P17870; NP_004032.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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