ARRB2 antibody (clone 3G1), anti-human
€435.00
In stock
SKU
AC-AT1201a
Catalog Number: AC-AT1201a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT1201a">Request Information
Background:
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Other Names:
Beta-arrestin-2, Arrestin beta-2, ARRB2, ARB2, ARR2
Antigen Type:
Recombinant Protein
Gene Name: ARRB2
Gene ID: 409
NCBI Accession: NP_001244257.1;NP_001244258.1;NP_001244259.1;NP_001244260.1;NP_004304.1;NP_945355.1
Primary Accession: P32121
Other Accession: BC007427
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Other Names:
Beta-arrestin-2, Arrestin beta-2, ARRB2, ARB2, ARR2
Antigen Type:
Recombinant Protein
Gene Name: ARRB2
Gene ID: 409
NCBI Accession: NP_001244257.1;NP_001244258.1;NP_001244259.1;NP_001244260.1;NP_004304.1;NP_945355.1
Primary Accession: P32121
Other Accession: BC007427
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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