Arrestin-C rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016],function:May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.,similarity:Belongs to the arrestin family.,tissue specificity:Inner and outer segments, and the inner plexiform regions of the retina.,

Synonyms: ARR3, ARRX, CAR, Arrestin-C, Cone arrestin, C-arrestin, cArr, Retinal cone arrestin-3, X-arrestin

Gene Name: ARR3

Gene ID: 407

SwissProt ID: P36575

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.