ARSA polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Description:
Rabbit IgG polyclonal antibody for Arylsulfatase A (ARSA) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
arsA antibody, ARSA_HUMAN antibody, arylsulfatase A antibody, Arylsulfatase A component C antibody, As 2 antibody, AS A antibody, As2 antibody, ASA antibody, AW212749 antibody, C230037L18Rik antibody, Cerebroside-sulfatase antibody, metachromatic leucodystrophy antibody, MGC125207 antibody, MLD antibody, OTTHUMP00000196546 antibody, OTTHUMP00000196548 antibody, TISP73 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ARSA (454-482aa QALKQLQLLKAQLDAAVTFGPSQVARGED), different from the related mouse sequence by six amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.