Artemis (DCLREIC) polyclonal, anti-human, mouse, rat antibody
€295.00
In stock
SKU
AC-ABV10233-100
Catalog Number: AC-ABV10233-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Artemis is a 78 kDa protein, belonging to metallo-beta-lactamase superfamily. It is involved in endonuclease activity to break DNA hairpins. It also has been reported that the C-terminus of Artemis interacts with DNA binding domain of Ligase IV directly. Ligase IV is a key enzyme in DNA repair and V(D)J recombination. Thus, Artemis is a novel protein that is involved in V(D)J recombination/DNA repair. Mutations cause human T-B-severe combined immunodeficiency associated with increased cellular radiosensitivity (RS-SCID).
Other Names:
DNA cross-link repair 1C protein, SNM1-like protein
Primary Accession: Q96SD1
Gene Name: DCLRE1C
Gene ID: 64421
Concentration (mg/ml): 0.5 mg/ml
Artemis is a 78 kDa protein, belonging to metallo-beta-lactamase superfamily. It is involved in endonuclease activity to break DNA hairpins. It also has been reported that the C-terminus of Artemis interacts with DNA binding domain of Ligase IV directly. Ligase IV is a key enzyme in DNA repair and V(D)J recombination. Thus, Artemis is a novel protein that is involved in V(D)J recombination/DNA repair. Mutations cause human T-B-severe combined immunodeficiency associated with increased cellular radiosensitivity (RS-SCID).
Other Names:
DNA cross-link repair 1C protein, SNM1-like protein
Primary Accession: Q96SD1
Gene Name: DCLRE1C
Gene ID: 64421
Concentration (mg/ml): 0.5 mg/ml
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