ASAH2 polyclonal, anti-human, mouse, rat

Background:
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).

Synonyms: BCDase, HNAC1, LCDase, N-CDase, NCDase

Cellular Location: Cell membrane Single-pass type II membrane protein

Immunogen:
Recombinant protein of human ASAH2

Gene Symbol: ASAH2

Gene ID: 56624

Swiss prot: Q9NR71

Calculated MW: 86kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.