ASAH2 Polyclonal Antibody

Background:
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Acylsphingosine deacylase 2, AI585898, ASAH2, ASAH2, BCDase, hCD, HNAC1, LCDase, MGC129777, mitochondrial ceramidase, N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2, N acylsphingosine amidohydrolase 2, N CDase, N-acylsphingosine amidohydrolase 2, N-CDase, NCDase, Neutral ceramidase soluble form, Non lysosomal ceramidase, Non-lysosomal ceramidase

Immunogen: Recombinant protein of human ASAH2

Swissprot: Q9NR71
Gene Accession: BC107105

Calculated MW: 86 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-79642/sc-79643/sc-68906