ASAH2 Polyclonal Antibody

Background:
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ASAH2, BCDase, HNAC1, LCDase, N-CDase, NCDase

Immunogen: Recombinant fusion protein of human ASAH2 (NP_001137446.1).

Swissprot: Q9NR71
Gene ID: 56624

Calculated MW: 81 kDa/85 kDa
Observed MW: 85 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.