ASB8 Polyclonal Antibody

Background:
ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.

Research Area: Cancer, Cell Biology

Synonyms:
Ankyrin repeat and SOCS box containing 8, Ankyrin repeat and SOCS box protein 8, ASB 8, ASB-8, ASB8, ASB8, FLJ21255, MGC5540, OTTHUMP00000237000, OTTHUMP00000237001, OTTHUMP00000237007, OTTHUMP00000237009, OTTHUMP00000237010, PP14212

Immunogen: Recombinant protein of human ASB8

Swissprot: Q9H765
Gene Accession: BC001321

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-109207