Asc (AL177) polyclonal, anti-human, mouse

Quantity: 100 µl

Description:
Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

Synonyms:
Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD, CARD5

Isotype: Rabbit Polyclonal

Immunogen:
Synthetic peptide corresponding to aa at the N-terminal human Asc.

Form: Purified, in PBS containing 10% glycerol and 0.02% sodium azide.

Specificity:
Recognizes human and mouse Asc.

Reactivity: human, mouse

Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Working DIlution: Optimal conditions must be determined individually for each application.

Storage: 2-8C immediate use, or -20C (aliquoted)