ASCC2 Polyclonal Antibody

Background:
ASCC2 (activating signal cointegrator 1 complex subunit 2), also known as ASC1P100, is a 757 amino acid protein that is ubiquitously expressed and contains one CUE domain.The gene encoding ASCC2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Research Area: Signal Transduction

Synonyms:
1700011I11Rik, 2610034L15Rik, Activating signal cointegrator 1 complex subunit 2, AI482016, ASC 1 complex subunit p100, ASC-1 complex subunit p100, ASC1P100, ASCC 2, Ascc2, ASCC2, AW046480, FLJ21588, OTTMUSP00000005258, p100, RGD1561422, RP23-280J3.3, Trip4 complex subunit p100

Immunogen: Synthetic peptide of human ASCC2

Swissprot: Q9H1I8
Gene Accession: NP_115580

Calculated MW: 86 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-86301/sc-86303