ASCL1 (Achaete-scute homolog 1) polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP2019B
Catalog Number: AC-AP2019B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB02899
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB02899
Applications: WB
Datasheet
Request Information
Background:
ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation.
Other Names:
Achaete-scute homolog 1, ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46, ASCL1, ASH1, BHLHA46, HASH1
Target/Specificity:
This ASCL1 (Achaete-scute homolog 1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-196 amino acids from the C-terminal region of human ASCL1 (Achaete-scute homolog 1).
Antigen Region:
166-196
Antigen Type: Synthetic Peptide
Gene Name: ASCL1 (HGNC:738)
Gene ID: 429
Primary Accession: P50553
NCBI Accession: NP_004307.2
Other Accession: P19359; Q02067; NP_004307
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation.
Other Names:
Achaete-scute homolog 1, ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46, ASCL1, ASH1, BHLHA46, HASH1
Target/Specificity:
This ASCL1 (Achaete-scute homolog 1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-196 amino acids from the C-terminal region of human ASCL1 (Achaete-scute homolog 1).
Antigen Region:
166-196
Antigen Type: Synthetic Peptide
Gene Name: ASCL1 (HGNC:738)
Gene ID: 429
Primary Accession: P50553
NCBI Accession: NP_004307.2
Other Accession: P19359; Q02067; NP_004307
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review