ASCL1 Polyclonal Antibody

Background:
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
Achaete scute complex homolog 1, Achaete scute complex homolog like 1, Achaete scute complex homologue 1, Achaete scute complex homologue like 1, Achaete scute complex like 1, Achaete scute family bHLH transcription factor 1, Achaete scute protein, Achaete-scute homolog 1, Ascl 1, ascl1, ASCL1, Ash 1, ASH-1, Ash1, bHLHa46, Class A basic helix-loop-helix protein 46, Hash 1, HASH1, Mammalian achaete scute homolog 1, Mammalian achaete scute homologue 1, Mash 1, Mash1

Immunogen: Synthetic peptide of human ASCL1

Swissprot: P50553
Gene Accession: NP_004307

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-13222/sc-48449/sc-13219/sc-28688