ASGR1 Polyclonal Antibody

Background:
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Signal Transduction, Tags and Cell Markers

Synonyms:
ASGP-R 1, ASGPR 1, ASGPR, ASGPR1, Asgr1, ASGR1, Asialoglycoprotein receptor 1, C type lectin domain family 4 member H1, C-type lectin domain family 4 member H1, CLEC4H1, Hepatic lectin H1, HL-1

Immunogen: Recombinant protein of human ASGR1

Swissprot: P07306
Gene Accession: BC032130

Calculated MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-13467/sc-28977