ASH2L Polyclonal Antibody

Background:
The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
ASH2L, ASH2, ASH2L1, ASH2L2, Bre2

Immunogen: Recombinant fusion protein of human ASH2L (NP_001098684.1).

Swissprot: Q9UBL3
Gene ID: 9070

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:20-1:50

Storage:
Store at -20°C. Avoid freeze / thaw cycles.