ASL antibody (clone 4C5-1F2), anti-human

Background:
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Other Names:
Argininosuccinate lyase, ASAL, Arginosuccinase, ASL

Antigen Type:
Recombinant Protein

Gene Name: ASL
Gene ID: 435
NCBI Accession: NP_000039.2;NP_001020114.1;NP_001020115.1;NP_001020117.1
Primary Accession: P04424
Other Accession: BC008195
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .