ASL Polyclonal Antibody

Background:
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Argininosuccinase, Argininosuccinate lyase, Arginosuccinase, ARLY, ASAL, ASL, EC 4.3.2.1

Immunogen: Recombinant protein of human ASL

Swissprot: P04424
Gene Accession: BC008195

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-68249/sc-68250/sc-68251/sc-98619