ASPN Polyclonal Antibody

Background:
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Signal Transduction

Synonyms:
ASPN, ASPN protein, ASPN, Asporin (LRR class 1), Asporin, Asporin proteoglycan, FLJ20129, LRR class 1, Periodontal ligament associated protein 1, Periodontal ligament-associated protein 1, PLAP 1, PLAP-1, PLAP1, SLRR 1C, SLRR1C, Small leucine rich protein 1C

Immunogen: Synthetic peptide of human ASPN

Swissprot: Q9BXN1
Gene Accession: NP_001180264

Calculated MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000 IHC 1:50-200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-70118/sc-70119