ASPN Polyclonal Antibody

Background:
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.

Research Area: Cancer, Signal Transduction

Synonyms:
ASPN, OS3, PLAP-1, PLAP1, SLRR1C, asporin

Immunogen: Recombinant fusion protein of human ASPN (NP_060150.4).

Swissprot: Q9BXN1
Gene ID: 54829

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.