Asporin / ASPN polyclonal, anti-human, mouse

Background:
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.

Other Names:
Asporin, Periodontal ligament-associated protein 1, PLAP-1, ASPN, PLAP1, SLRR1C

Antigen Types:
Synthetic Peptide

Gene Name:
ASPN
Gene ID:
54829
Primary Accession: Q9BXN1
Other Accession: NP_060150;54829;