ASPSCR1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Synonyms: ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9

Cellular Location: Cytoplasm Endomembrane system Endoplasmic reticulum-Golgi intermediate compartment membrane Nucleus Peripheral membrane protein

Immunogen:
Recombinant protein of human ASPSCR1

Gene Symbol: ASPSCR1

Gene ID: 79058

Swiss prot: Q9BZE9

Calculated MW: 60kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200, IP 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.