ASS1 Polyclonal Antibody

Background:
ASS1 is a rate-limiting enzyme in the urea cycle. Citrullinemia type I is an autosomal recessive disorder that is caused by a deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS1). Deficiency of ASS1 shows various clinical manifestations encompassing severely affected patients with fatal neonatal hyperammonemia as well as asymptomatic individuals with only a biochemical phenotype.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Argininosuccinate synthase 1, Argininosuccinate synthase, Argininosuccinate synthetase 1, ASS, Ass-1, ass1, ASSA, ASSY, Citrulline aspartate ligase, Citrulline--aspartate ligase, CTLN1

Immunogen: Fusion protein of human ASS1

Swissprot: P00966
Gene Accession: BC021676

Calculated MW: 47 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.