Ataxin-2L rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],PTM:Arg-361 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Thrombopoietin triggers the phosphorylation on tyrosine residues in a way that is dependent on MPL C-terminal domain.,sequence caution:Exon duplication.,similarity:Belongs to the ataxin-2 family.,subunit:Interacts with MPL/TPOR and EPOR and dissociates after ligand stimulation.,tissue specificity:Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells.,

Synonyms: ATXN2L, A2D, A2LG, A2LP, A2RP, Ataxin-2-like protein, Ataxin-2 domain protein, Ataxin-2-related protein

Gene Name: ATXN2L

Gene ID: 11273

SwissProt ID: Q8WWM7

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.