ATBF1 antibody (clone 3B1), anti-human
€435.00
In stock
SKU
AC-AT1221a
Catalog Number: AC-AT1221a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT1221a">Request Information
Background:
This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.
Other Names:
Zinc finger homeobox protein 3, AT motif-binding factor 1, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3, ZFHX3, ATBF1
Antigen Type:
Recombinant Protein
Gene Name: ZFHX3
Gene ID: 463
NCBI Accession: NP_001158238.1;NP_008816.3
Primary Accession: Q15911
Other Accession: NM_006885
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.
Other Names:
Zinc finger homeobox protein 3, AT motif-binding factor 1, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3, ZFHX3, ATBF1
Antigen Type:
Recombinant Protein
Gene Name: ZFHX3
Gene ID: 463
NCBI Accession: NP_001158238.1;NP_008816.3
Primary Accession: Q15911
Other Accession: NM_006885
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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