ATF1 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.

Description:
Rabbit IgG polyclonal antibody for Cyclic AMP-dependent transcription factor ATF-1 (ATF1) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
Activating transcription factor 1 antibody, ATF 1 antibody, atf1 antibody, ATF1 EWS fusion gene antibody, ATF1 FUS fusion gene antibody, ATF1_HUMAN antibody, cAMP dependent transcription factor 1 antibody, cAMP-dependent transcription factor ATF-1 antibody, Cyclic AMP dependent transcription factor ATF 1 antibody, Cyclic AMP dependent transcription factor ATF1 antibody, Cyclic AMP-dependent transcription factor ATF-1 antibody, EWS AFT1 antibody, FUS ATF 1 antibody, FUS/ATF 1 antibody, Protein TREB36 antibody, RNA binding protein activating transcription factor 1 fusion protein antibody, TREB 36 antibody, TREB36 antibody, TREB36 protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.