ATF2 C-terminal region polyclonal, anti-human, mouse, rat, rabbit, dog, guinea pig, horse, bovine

Background:
This is a rabbit polyclonal antibody against ATF2. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein.

Other Names:
Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF2, CREB2, CREBP1

Target/Specificity:
ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.

Immunogen:
The immunogen for anti-ATF2 antibody: synthetic peptide directed towards the C terminal of human ATF2

Gene Name:
ATF2
Gene Name:
1386
Swissprot ID: P15336-2
NCBI Accession:
NP_001871
Primary Accession: P15336
Other Accession: P15336-2;NP_001871;NM_001880
Purification: Protein A purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.