ATF2 polyclonal (Center T339), anti-human, mouse

ATF2 polyclonal (Center T339), anti-human, mouse

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In stock
SKU
AC-AP16866c
Catalog Number: AC-AP16866c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36858
Applications: WB
Datasheet

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Background:
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined

Other Names:
Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF2, CREB2, CREBP1

Target/Specificity:
This ATF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human ATF2.

Antigen Region:
318-347

Antigen Type: Synthetic Peptide

Gene Name: ATF2
Gene ID: 1386
Primary Accession: P15336
NCBI Accession: NP_001243019.1;NP_001243020.1;NP_001243021.1;NP_001243022.1;NP_001243023.1;NP_001871.2
Other Accession: NP_001871.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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