ATF3 polyclonal, anti-human, mouse, rat

Background:
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

Synonyms: ATF3_HUMAN, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, Activating transcription factor 3

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human ATF3

Gene Symbol: ATF3

Gene ID: 467

Swiss prot: P18847

Calculated MW: 21kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.