ATF3 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP16577b
Catalog Number: AC-AP16577b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30340
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30340
Applications: WB, FC
Datasheet
Request Information
Background:
Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Other Names:
Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3
Target/Specificity:
This ATF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human ATF3.
Antigen Region:
140-168
Antigen Type: Synthetic Peptide
Gene Name: ATF3 {ECO:0000303|PubMed:7515060, ECO:0000312|HGNC:HGNC:785}
Gene ID: 467
Primary Accession: P18847
NCBI Accession: NP_001025458.1;NP_001035709.1;NP_001193413.2;NP_001193415.1;NP_001193417.2;NP_001665.1
Other Accession: P29596; Q60765; Q2KII1; NP_001025458.1; NP_001665.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Other Names:
Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3
Target/Specificity:
This ATF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human ATF3.
Antigen Region:
140-168
Antigen Type: Synthetic Peptide
Gene Name: ATF3 {ECO:0000303|PubMed:7515060, ECO:0000312|HGNC:HGNC:785}
Gene ID: 467
Primary Accession: P18847
NCBI Accession: NP_001025458.1;NP_001035709.1;NP_001193413.2;NP_001193415.1;NP_001193417.2;NP_001665.1
Other Accession: P29596; Q60765; Q2KII1; NP_001025458.1; NP_001665.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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