ATF4 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12242c
Background:
This gene encodes a transcription factor that wasoriginally identified as a widely expressed mammalian DNA bindingprotein that could bind a tax-responsive enhancer element in theLTR of HTLV-1. The encoded protein was also isolated andcharacterized as the cAMP-response element binding protein 2(CREB-2). The protein encoded by this gene belongs to a family ofDNA-binding proteins that includes the AP-1 family of transcriptionfactors, cAMP-response element binding proteins (CREBs) andCREB-like proteins. These transcription factors share a leucinezipper region that is involved in protein-protein interactions,located C-terminal to a stretch of basic amino acids that functionsas a DNA binding domain. Two alternative transcripts encoding thesame protein have been described. Two pseudogenes are located onthe X chromsome at q28 in a region containing a large invertedduplication.
Other Names:
Cyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, DNA-binding protein TAXREB67, Tax-responsive enhancer element-binding protein 67, TaxREB67, ATF4, CREB2, TXREB
Gene Name: ATF4 {ECO:0000303|PubMed:2516827, ECO:0000312|HGNC:HGNC:786}
Gene ID: 468
Primary Accession: P18848
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a transcription factor that wasoriginally identified as a widely expressed mammalian DNA bindingprotein that could bind a tax-responsive enhancer element in theLTR of HTLV-1. The encoded protein was also isolated andcharacterized as the cAMP-response element binding protein 2(CREB-2). The protein encoded by this gene belongs to a family ofDNA-binding proteins that includes the AP-1 family of transcriptionfactors, cAMP-response element binding proteins (CREBs) andCREB-like proteins. These transcription factors share a leucinezipper region that is involved in protein-protein interactions,located C-terminal to a stretch of basic amino acids that functionsas a DNA binding domain. Two alternative transcripts encoding thesame protein have been described. Two pseudogenes are located onthe X chromsome at q28 in a region containing a large invertedduplication.
Other Names:
Cyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, DNA-binding protein TAXREB67, Tax-responsive enhancer element-binding protein 67, TaxREB67, ATF4, CREB2, TXREB
Gene Name: ATF4 {ECO:0000303|PubMed:2516827, ECO:0000312|HGNC:HGNC:786}
Gene ID: 468
Primary Accession: P18848
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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