ATG10 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1815a
Catalog Number: AC-AP1815a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7550
Applications: IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7550
Applications: IHC-P
Datasheet
Request Information
Background:
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG10 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG10 also is able to directly interact either with ATG5 or ATG7.
Other Names:
Ubiquitin-like-conjugating enzyme ATG10, 632-, Autophagy-related protein 10, APG10-like, ATG10, APG10L
Target/Specificity:
This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.
Antigen Region:
15-45
Antigen Type: Synthetic Peptide
Gene Name: ATG10
Gene ID: 83734
Primary Accession: Q9H0Y0
NCBI Accession: NP_001124500.1;NP_113670.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG10 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG10 also is able to directly interact either with ATG5 or ATG7.
Other Names:
Ubiquitin-like-conjugating enzyme ATG10, 632-, Autophagy-related protein 10, APG10-like, ATG10, APG10L
Target/Specificity:
This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.
Antigen Region:
15-45
Antigen Type: Synthetic Peptide
Gene Name: ATG10
Gene ID: 83734
Primary Accession: Q9H0Y0
NCBI Accession: NP_001124500.1;NP_113670.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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