ATG16L1 Polyclonal Antibody

Background:
ATG16L1 (Autophagy Related 16 Like 1) is a Protein Coding gene. Diseases associated with ATG16L1 include Inflammatory Bowel Disease 10 and Inflammatory Bowel Disease. Among its related pathways are Autophagy Pathway and Senescence and Autophagy in Cancer. GO annotations related to this gene include identical protein binding. An important paralog of this gene is ATG16L2.The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms:
A16L1, APG16 like 1, APG16-like 1, APG16L, APG16L beta, ATG16 autophagy related 16 like 1, ATG16 autophagy related 16-like 1 (S. cerevisiae), ATG16A, ATG16L, Atg16l1, Autophagy related protein 16 1, Autophagy-related protein 16-1, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, OTTHUMP00000164391, OTTHUMP00000164393, OTTHUMP00000165876, OTTHUMP00000165877, WD repeat domain 30, WDR30

Immunogen: Synthetic peptide of human ATG16L1

Swissprot: Q676U5
Gene Accession: NP110430

Calculated MW: 68 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:2000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.