ATG16L1 Polyclonal Antibody

Background:
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms:
ATG16L1, APG16L, ATG16A, ATG16L, IBD10, WDR30

Immunogen: A synthetic peptide of human ATG16L1 (NP_110430.5).

Swissprot: Q676U5
Gene ID: 55054

Calculated MW: 47 kDa/49 kDa/53 kDa/66 kDa/68 kDa
Observed MW: 72 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.