ATG4A Polyclonal Antibody

Background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
AI627006, APG4 autophagy 4 homolog A, Apg4a, ATG4 autophagy related 4 homolog A (S. cerevisiae), ATG4 autophagy related 4 homolog A, ATG4A, ATG4A, Atg4al, AUT like 2 cysteine endopeptidase, AUT-like 2 cysteine endopeptidase, Autl2, Autophagin 2, Autophagin-2, Autophagy related 4A cysteine peptidase, Autophagy related cysteine endopeptidase 2, Autophagy related protein 4 homolog A, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, AV169859, Cysteine protease ATG4A, hAPG4A, MGC107179

Immunogen: Synthetic peptide of human ATG4A

Swissprot: Q8WYN0
Gene Accession: NP_443168

Calculated MW: 45 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-131433/sc-131435/sc-131432