ATG4D Polyclonal Antibody

Background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
9830134P12Rik, APG4 autophagy 4 homolog D, APG4 D, APG4, S. cerevisiae, homolog of, D, APG4D, ATG4 autophagy related 4 homolog D (S. cerevisiae), Atg4d, ATG4D, Atg4dl, AUT like 4 cysteine endopeptidase, AUT-like 4 cysteine endopeptidase, AUTL4, Autophagin 4, Autophagin-4, autophagy 4, S. cerevisiae, homolog of, D, autophagy related 4D, cysteine peptidase, Autophagy related cysteine endopeptidase 4, Autophagy related protein 4 homolog D, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D, Cysteine protease involved in autophagy, MGC31226

Immunogen: Recombinant protein of human ATG4D

Swissprot: Q86TL0
Gene Accession: BC007639

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.