ATG5 (3C7) Mouse mAb

Background:
Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

Cellular localization: Cytoplasm, Membrane

Specificity: Human

Alternative Names:
APG5, APG5L, ASP, Autophagy protein 5 antibody

Immunogen: Recombinant Protein

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: WB  1:5,000-10,000, IHC 1:100-200

Observed band: 55kDa

GeneID: 9494

Swiss-Prot No.: Q9H1Y0

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only