ATG5 Polyclonal Antibody

Background:
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5

Immunogen: Recombinant fusion protein of human ATG5 (NP_004840.1).

Swissprot: Q9H1Y0
Gene ID: 9474

Calculated MW: 22 kDa/32 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.