ATG5 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene| in combination with autophagy protein 12| functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes| including autophagic vesicle formation| mitochondrial quality control after oxidative damage| negative regulation of the innate antiviral immune response| lymphocyte development and proliferation| MHC II antigen presentation| adipocyte differentiation| and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Cell biology, Metabolism

Synonyms: ATG5, Autophagy protein 5, APG5-like, Apoptosis-specific protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year