ATG7 polyclonal, anti-human, mouse, rat

Background:
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

Synonyms: APG7-LIKE, APG7L, GSA7

Cellular Location: Cytoplasm Preautophagosomal structure

Immunogen:
Recombinant protein of human ATG7

Gene Symbol: ATG7

Gene ID: 10533

Swiss prot: O95352

Calculated MW: 78kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.