ATG9A polyclonal, anti-human

ATG9A polyclonal, anti-human

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In stock
SKU
AC-AP1814i
Catalog Number: AC-AP1814i
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13941
Applications: IHC-P, WB
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Background:
Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

Other Names:
Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1

Target/Specificity:
This ATG9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723~753 amino acids surrounding S738 of human APG9L1.

Antigen Region:
723-753

Antigen Type: Synthetic Peptide

Gene Name: ATG9A {ECO:0000303|PubMed:20124090, ECO:0000312|HGNC:HGNC:22408}
Gene ID: 79065
Primary Accession: Q7Z3C6
NCBI Accession: NP_001070666.1;NP_076990.4
Other Accession: Q5FWU3; Q3T904; Q68FE2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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