ATG9A polyclonal (C-term), anti-human

Background:
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.

Other Names:
Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1

Target/Specificity:
This ATG9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-746 amino acids from the C-terminal region of human ATG9A.

Antigen Region:
717-746

Antigen Type: Synthetic Peptide

Gene Name: ATG9A {ECO:0000303|PubMed:20124090, ECO:0000312|HGNC:HGNC:22408}
Gene ID: 79065
Primary Accession: Q7Z3C6
NCBI Accession: NP_001070666.1;NP_076990.4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.