ATIC Antibody (C-term) Blocking Peptide

Background:
ATIC is a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity.

Other Names:
Bifunctional purine biosynthesis protein PURH, Phosphoribosylaminoimidazolecarboxamide formyltransferase, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase, AICAR transformylase, IMP cyclohydrolase, ATIC, IMP synthase, Inosinicase, ATIC, PURH

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6979b was selected from the C-term region of human ATIC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: ATIC (HGNC:794)

Gene ID: 471
Primary Accession: P31939
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.